Epoetin and darbepoetin belong to a group of medications called 'Erythropoiesis Stimulating Agents'. J Assoc Physicians India. Pankaj Thakur. This large, phase III study demonstrates comparable efficacy of DA Q2W and EA QW. Aranesp vs Epogen – Comparison of Uses & Side Effects. Patients mostly reported TEAEs of mild-to-moderately severe in nature except one (1.58%) from the EPO group who experienced severe TEAEs.
The erythropoietin analogue darbepoetin-alpha carries two additional glycosylation sites that permit a higher degree of glycosylation. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. J Clin Oncol. Hedenus M, Hansen S, Taylor K, et al. As noted in the previous report, transfusion-related adverse events are uncommon. where patients were allocated by alternation, the use of case record numbers, dates of birth or day of week, and any other procedure that is transparent before allocation, such as an open list of random numbers. The results of our study demonstrated that efficacy and safety of DA-α (manufactured by Hetero Biopharma), when administered at a reduced dose frequency, is similar to EPO for treating renal anemia in Indian patients with ESRD undergoing dialysis. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Listing a study does not mean it has been evaluated by the U.S. Federal Government. There are several evidence-based guidelines assessing the efficacy of erythropoietin for treating patients with solid tumors receiving chemotherapy and summarizing evidence for reduced transfusion requirements. SAS® Version 9.4 (SAS Institute Inc., USA) was used to perform all statistical analyses. General information: title, authors, source, contact address, year of publication, duplicate publications, setting, funding.
It is rare, but it is possible for an exceptional manuscript to be accepted at this stage. by measuring percentage of cases with mean Hemoglobin concentration between 11-12 gm/dl and measuring mean monthly hemoglobin concentrations.
Impact of hemoglobin level and use of recombinant erythropoietin on efficacy of preoperative chemoradiation therapy for squamous cell carcinoma of the oral cavity and oropharynx.
To compare the effectiveness of darbepoetin alfa with epoetin alfa (recombinant human erythropoietin [rHuEPO]) for achieving transfusion independence and increasing hemoglobin concentrations in critically ill patients. Patients: sampling, exclusion criteria, sample size, baseline characteristics, similarity of groups at baseline, diagnostic criteria, withdrawals, losses to follow up.
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